TABLE 1.
Genes associated with TMP susceptibility in E. coli K-12 W3110 strains.
| Gene name | TMP MICs (μg ml–1) of wild-type strains | TMP MICs (μg ml–1) of gene deletion mutants | TMP MICs (μg ml–1) of complemented strains | TMP MICs (μg ml–1) of overexpressed strains |
| mgrB | 0.16 | 1.28 | 0.16 | 0.16 |
| ymjC | 0.16 | 0.32 | 0.32 | 0.16 |
| rcsC | 0.16 | 0.32 | 0.16 | 0.16 |
| tehB | 0.16 | 0.32 | 0.16 | 0.16 |
| rfaH | 0.16 | 0.08 | 0.08 | 0.16 |
| pgpA | 0.16 | 0.16 | 0.64 | 0.64 |
| cysB | 0.16 | 0.64 | 0.16 | 0.16 |
| torR | 0.16 | 0.64 | 0.64 | 0.16 |
| phoP | 0.16 | 0.08 | 0.16 | 0.16 |
| acrB | 0.16 | 0.04 | 0.08 | 0.16 |
| yhfK | 0.16 | 0.16 | 0.08 | 0.08 |
| acrA | 0.16 | 0.02 | 0.04 | 0.16 |
| phoQ | 0.16 | 0.08 | 0.16 | 0.16 |
Cultures were incubated overnight at 37°C on LB with 10 μM IPTG.