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. 2021 Aug 2;30:100385. doi: 10.1016/j.jbo.2021.100385

Table 3.

Univariate and multivariable Cox regression analyses for independent prognostic factors affecting cause-specific survival in the entire cohort (n = 277).

Variables Unadjusted Adjusted
HR 95%CI P HR 95%CI P
Age (years)
 <25 1 1
 ≥25 2.305 1.558–3.411 <0.001 2.210 1.490–3.279 <0.001
Gender
 Male 1
 Female 1.013 0.687–1.493 0.948
Race/ethnicity
 White 1 1
 Black 2.184 1.058–4.506 0.035 1.595 0.734–3.467 0.238
 Other 1.199 0.656–2.192 0.554 0.862 0.458–1.622 0.645
Tumor location
 Axial 1
 Extremity 0.989 0.679–1.440 0.952
Tumor size
 ≤5 cm 1 1
 >5–10 cm 0.386 0.177–0.844 0.017 0.420 0.186–0.944 0.036
 >10 cm 0.555 0.259–1.192 0.131 0.586 0.263–1.306 0.191
 Unknown 0.743 0.342–1.612 0.452 0.568 0.250–1.290 0.176
Regional nodal status
 Negative 1
 Positive 1.105 0.678–1.802 0.688
 Unknown 0.920 0.441–1.919 0.824
The sites of distant metastases
 Bone yes vs. no 2.183 1.482–3.216 <0.001 1.903 1.254–2.887 0.002
 Lung yes vs. no 0.833 0.567–1.223 0.351
 Liver yes vs. no 2.531 1.102–5.814 0.029 1.436 0.582–3.541 0.433
 Brain yes vs. no 0.906 0.288–2.855 0.866
 Distant lymph node yes vs. no 1.142 0.596–2.189 0.69
The number of distant metastases
 1 1 1
 ≥2 2.063 1.376–3.095 <0.001 1.458 0.943–2.255 0.090

CI, confidence interval; HR, hazard ratio.