Table 1.
Main characteristics of included studies.
| Study | Year | Country | Ethnicity | Case/control | Case | Control | HWE | ||
|---|---|---|---|---|---|---|---|---|---|
| Mutant allele | Wild allele | Mutant allele | Wild allele | ||||||
| rs26653 (G/C) | |||||||||
| Anamika | 2017 | India | Indian | 911/1120 | 893 | 929 | 1030 | 1210 | 0.60 |
| Andrzej | 2018 | Poland | Polish | 461/454 | 252 | 670 | 256 | 652 | 0.02 |
| Fu | 2018 | China | Han | 143/149 | 141 | 145 | 122 | 176 | >0.05 |
| Josefin | 2013 | Sweden | Caucasian | 1863/1748 | 1155 | 2571 | 909 | 2587 | NA |
| Marta | 2018 | Poland | Polish | 127/101 | 44 | 210 | 70 | 132 | NA |
| rs30187 (C/T) | |||||||||
| Anamika | 2017 | India | Indian | 911/1120 | 911 | 911 | 941 | 1299 | 0.59 |
| Andrzej | 2018 | Poland | Polish | 461/454 | 311 | 611 | 302 | 606 | 0.67 |
| Anne | 2011 | UK | Caucasian | 76/5200 | 58 | 94 | 3432 | 6968 | >0.05 |
| Josefin | 2013 | Sweden | Caucasian | 1863/1748 | 1416 | 2310 | 1189 | 2307 | NA |
| Olivia | 2016 | Romania | Caucasian | 88/139 | 69 | 107 | 89 | 189 | >0.05 |
| rs27524 (G/A) | |||||||||
| Andrzej | 2018 | Poland | Polish | 461/454 | 307 | 615 | 311 | 597 | 0.83 |
| Bergboer | 2012 | Netherlands | Caucasian | 215/450 | 172 | 258 | 295 | 605 | >0.05 |
| Fu | 2018 | China | Han | 143/149 | 129 | 157 | 113 | 185 | >0.05 |
| Josefin | 2013 | Sweden | Caucasian | 1863/1748 | 1453 | 2273 | 1259 | 2237 | NA |
| Yang | 2013 | China | Han | 974/1181 | 885 | 1063 | 945 | 1417 | 0.58 |
Note: HWE: Hardy-Weinberg equilibrium.