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. 2021 Aug 3;2021:6389568. doi: 10.1155/2021/6389568

Figure 5.

Figure 5

miR-623 attenuates TBHP-induced apoptosis and inflammation via TXNIP. (a) Western blot analysis of TXNIP expression in NP cells induced by TBHP with or without miR-623 mimic transfection. (b) Western blot analyses of TXNIP, BAX, BCL2, cleaved caspase-3, collagen II, iNOS, MMP13, and IL-1β in NP cells induced by TBHP with or without TXNIP overexpression and/or miR-623 mimic transfection. (c, d) Quantification analysis of IL-1β and IL-6 mRNA expression in NP cells induced by TBHP with or without TXNIP overexpression and/or miR-623 mimic transfection. (e) Quantification analysis of the secretion of IL-6 in culture medium of NP cells induced by TBHP with or without TXNIP overexpression and/or miR-623 mimic transfection. ∗∗∗P < 0.001. P values were analyzed by two-way ANOVA.