Table 7.

Variance analysis of the Box–Behnken test.

Variance source	Sum of squares	Degree of freedom	Mean square	F value	P value	Significance
Model	0.12	9	0.013	23.10	0.0002	Significant
A	2.835E − 005	1	2.835E − 005	0.050	0.8303
B	6.258E − 004	1	6.258E − 004	1.09	0.3306
C	3.103E − 005	1	3.103E − 005	0.054	0.8226
AB	7.323E − 003	1	7.323E − 003	12.79	0.0090
AC	2.189E − 003	1	2.189E − 003	3.82	0.0915
BC	1.904E − 003	1	1.904E − 003	3.32	0.1111
A 2	0.066	1	0.066	115.22	<0.0001
B 2	4.495E − 003	1	4.495E − 003	7.85	0.0265
C 2	0.028	1	0.028	48.81	0.0002
Residual	4.009E − 003	7	5.727E − 004
Lack of fit	2.714E − 003	3	9.047E − 004	2.79	0.1731	Not significant
Pure error	1.295E − 003	4	3.238E − 004
Cor total	0.12	16
R 2	0.9674
R 2 Adj	0.9256