Table 2.
Comparison of differentially expressed mRNAs with NP-related phenotypes in RGD database.
| Gene | Comparison1 p value |
Comparison1 log2 FC |
Comparison2 p value |
Comparison2 log2 FC |
NSD | Neuralgia | Pain | Hyperalgesia | Inflammation |
|---|---|---|---|---|---|---|---|---|---|
| Atf3 | 3.20E − 21 | 4.045819 | 0.001948 | -1.442530 | √ | ||||
| Gal | 7.18E − 11 | 3.829123 | 0.003094 | -2.022188 | √ | √ | √ | ||
| Cacna2d1 | 4.61E − 08 | 1.261635 | 0.014522 | -0.607313 | √ | √ | √ | ||
| Nos1 | 3.00E − 07 | 1.799434 | 0.030345 | -0.835820 | √ | √ | √ | ||
| Reg3b | 3.49E − 07 | 4.162273 | 0.004735 | -2.012063 | √ | ||||
| Adcyap1 | 6.55E − 06 | 1.235189 | 0.019065 | -0.639252 | √ | ||||
| Gch1 | 6.40E − 05 | 1.984458 | 0.047527 | -0.959824 | √ | ||||
| Sdc1 | 7.90E − 05 | 2.078746 | 0.013891 | -1.300921 | √ | ||||
| Il1a | 0.000680 | 7.930640 | 0.000627 | -8.012905 | √ | √ | |||
| Tnfaip6 | 0.000696 | 2.455342 | 0.003988 | -2.044203 | √ | ||||
| Ctss | 0.004446 | 0.836964 | 0.017493 | -0.774995 | √ | √ | √ | ||
| Ltf | 0.010002 | 7.393181 | 0.009157 | -7.477871 | √ | ||||
| Spp1 | 0.010235 | 0.605711 | 0.036589 | -0.494265 | √ | √ | |||
| Cyp11a1 | 0.026784 | -7.823132 | 0.004030 | 8.228974 | √ |
Comparison1 represents the sham-operated group vs. CCI group. Comparison2 represents the CCI group vs. CC-exercised group; FC: fold change; NDS: nervous system disease.