Table 2.
Simultaneously estimated bivariate correlations obtained from a saturated path analysis
| Health-related quality of life subscale | Dystonia severity | Tremor | Depression | Generalised anxiety | Social anxiety | Age | Sex |
|---|---|---|---|---|---|---|---|
| General health | −0.09 (−0.17 to −0.01) |
−0.05 (−0.13 to 0.03) |
−0.50*** (−0.57 to −0.44) |
−0.40*** (−0.47 to −0.33) |
−0.31*** (−0.39 to −0.22) |
0.07 (−0.01 to 0.15) |
−0.04 (−0.12 to 0.04) |
| Physical functioning | −0.14*** (−0.22 to −0.06) |
−0.14*** (−0.22 to −0.06) |
−0.47*** (−0.54 to −0.4) |
−0.27*** (−0.35 to −0.18) |
−0.27*** (−0.36 to −0.18) |
−0.07 (−0.15 to 0.01) |
−0.07 (−0.15 to 0.002) |
| Physical role functioning | −0.24*** (−0.32 to −0.16) |
−0.01 (−0.09 to 0.07) |
−0.49*** (−0.55 to −0.43) |
−0.35*** (−0.42 to −0.28) |
−0.26*** (−0.34 to −0.2) |
0.08 (0.003 to 0.16) |
−0.06 (−0.14 to 0.02) |
| Pain | −0.10 (−0.19 to −0.001) |
−0.11** (−0.19 to −0.03) |
−0.52*** (−0.58 to −0.45) |
−0.38*** (−0.46 to −0.31) |
−0.23*** (−0.32 to −0.14) |
0.11 (0.03 to 0.2) |
−0.07 (−0.15 to 0.01) |
| Energy/fatigue | −0.09 (−0.17 to −0.01) |
−0.09 (−0.18 to −0.01) |
−0.66*** (−0.71 to −0.61) |
−0.45*** (−0.51 to −0.38) |
−0.34*** (−0.41 to −0.27) |
0.13** (0.05 to 0.21) |
−0.05 (−0.13 to 0.03) |
| Emotional well-being | −0.11 (−0.2 to −0.02) |
−0.002 (−0.08 to 0.08) |
−0.72*** (−0.76 to −0.67) |
−0.68*** (−0.72 to −0.63) |
−0.41*** (−0.49 to −0.33) |
0.15*** (0.07 to 0.22) |
0.01 (−0.07 to 0.09) |
| Emotional role functioning | −0.17*** (−0.26 to −0.09) |
0.02 (−0.06 to 0.1) |
−0.49*** (−0.56 to −0.42) |
−0.42*** (−0.48 to −0.35) |
−0.32*** (−0.4 to −0.24) |
0.11 (0.03 to 0.19) |
0.01 (−0.07 to 0.09) |
| Social functioning | −0.23*** (−0.32 to −0.15) |
−0.004 (−0.09 to 0.08) |
−0.67*** (−0.72 to −0.62) |
−0.44*** (−0.5 to −0.37) |
−0.42*** (−0.5 to −0.35) |
0.10 (0.02 to 0.18) |
0.05 (−0.03 to 0.14) |
Path analysis: Numerical estimates and 95% CIs as indicators of the strength of the relationships between the eight HR-QoL subscales (RAND 36-Item Health Survey) and dystonia severity (BFMDRS), tremor, severity of depression (HADS-D), severity of generalised anxiety (HADS-A), severity of social anxiety (LSAS), age and sex in 603 patients with dystonia.
**
Bonferroni corrected alpha ≤ 0.006;
***
p ≤ 0.001
BFMDRS, Burke-Fahn-Marsden Dystonia Rating Scale; HADS, Hospital Anxiety and Depression Scale; HR-QoL, health-related quality of life; LSAS, Liebowitz Social Anxiety Scale.