Table 2.
Recurrence prediction using gene expression in TCGA training cohort.
Each gene in TCGA | Sensitivity | Specificity | AUC (95% CI) | HR | HR 95%CI | p-value |
---|---|---|---|---|---|---|
RLTPR | 72% | 65% | 0.71 (0.59-0.83) | 8.66 | 2.51-29.87 | 0.001 |
SLFN13 | 74% | 79% | 0.78 (0.67-0.89) | 3.33 | 1.83-6.05 | <0.001 |
MIR4500HG | 76% | 68% | 0.74 (0.62-0.85) | 3.68 | 1.59-8.51 | 0.002 |
HYDIN | 65% | 74% | 0.72 (0.61-0.83) | 2.16 | 1.37-3.42 | 0.001 |
TPRG1 | 74% | 76% | 0.75 (0.64-0.86) | 0.16 | 0.06-0.47 | 0.001 |
Five-gene combine | 85% | 85% | 0.91 (0.84-0.98) | 19.18 | 6.36-57.85 | <0.001 |