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The combination of five genes showed a strong association with tumor early recurrence in validation cohorts.
| Cohorts | Sensitivity | Specificity | AUC (95% CI) | HR | HR 95%CI | p-value |
|---|---|---|---|---|---|---|
| XYEYY | 89% | 82% | 0.82 (0.61-0.99) | 7.91 | 3.34-35.9 | <0.001 |
| GSE116959 | 81% | 75% | 0.84 (0.70-0.99) | 8.23 | 2.74-38.49 | 0.008 |
| GSE37745 | 76% | 65% | 0.71 (0.56-0.87) | 5.75 | 2.3-25.58 | 0.002 |
| GSE32863 | 70% | 70% | 0.80 (0.61-0.98) | 7.86 | 1.66-37.32 | 0.009 |
| GSE31210 | 61% | 54% | 0.62 (0.52-0.73) | 1.88 | 1.21-3.765 | 0.03 |
