Table 4.

Comparison of general practitioner pharmacological management in period one and period two for knee and hip OA.

	Knee OA Rate per 100 knee OA problems managed (95% CI)				Hip OA Rate per 100 hip OA problems managed (95% CI)
	2005-10		2010-16		2005-10		2010-16
	N	n=3,058	N	n=4,156	N	n=1,106	N	n=1,492
All medication
All	2,365	77•3 (74•5-80•2)	3,086	74•3 (71•7-76•8)	836	75•6 (71•4-80•0)	1,120	75•1 (70•8-79•4)
New	529	78•7 (73•2-84•2)	722	75•2 (70•5-80•0)	208	73•2 (64•7-81•8)	258	69•5 (62•2-76•9)
Prescribed	1,818	59•5 (56•9-62•0)	2,444	58•8 (56•5-61•1)	717	64•8 (60•5-69•2)	992	66•5 (62•3-70•6)
Advised over counter	344	11•3 (9•8-12•7)	443	10•7 (9•5-11•9)	96	8•7 (6•8-10•6)	100	6•7 (5•3-8•1)
Supplied	203	6•6 (5•3-8•0)	199	4•8 (3•9-5•7)	23	2•1 (1•1-3•1)	28	1•9 (1•0-2•7)
NSAIDs
All	862	28•2 (26•4-29•9)	853	20•5 (19•2-21•9) *	266	24•1 (21•4-26•7)	261	17•5 (15•5-19•5) *
New	215	32•0 (28•4-35•6)	218	22•7 (20•0-25•4) *	70	24•6 (19•5-29•8)	66	17•8 (13•7-21•8)
Paracetamol
All	693	22•7 (21•0-24•3)	1,096	26•4 (24•9-27•9) *	258	23•3 (20•7-25•9)	357	23•9 (21•5-26•4)
New	156	25•7 (22•3-29•1)	232	24•2 (21•4-26•9)	79	27•8 (22•5-33•1)	101	27•2 (22•5-32•0)
Opioids
All	316	10•3 (9•2-11•5)	621	14•9 (13•7-16•2) *	218	19•7 (17•0-22•5)	382	25•6 (22•8-28•4) *
New	21	3•1 (1•8-4•5)	65	6•8 (5•1-8•5) *	27	9•5 (5•6-13•4)	36	9•7 (6•5-13•0)
Glucosamine
All	148	4•8 (4•0-5•6)	74	1•8 (1•4-2•2) *	36	3•3 (2•2-4•3)	10	0•7 (0•3-1•1) *
New	54	8•0 (6•0-10•1)	26	2•7 (1•6-3•8) *	19	6•7 (3•8-9•6)	3	0•8 (0•0-1•7) *

* significant difference compared with 2005-2010 time period.

NSAIDS=non steroidal anti-inflammatory drugs.