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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Biochimie. 2021 Jan 12;182:73–84. doi: 10.1016/j.biochi.2020.12.022

Fig. 1. Alcohol exposure results in fibrosis induction in Oncopig livers.

Fig. 1.

Representative images of Masson’s trichrome-stained Oncopig liver sections (2.5X) histologically graded for fibrosis using a porcine adapted METAVIR scheme. (A) Control, histologically normal Oncopig liver with normal pre-existing fibrous septa and associated classic hepatic-lobule architecture. (B) F3 fibrosis grade demonstrating numerous inter- and intra-lobular dissecting fibrous septa present at 8 weeks post-induction. (C) METAVIR inflammation, fibrosis scores, and percent fibrosis for each samples 8 weeks post-induction.