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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Biochimie. 2021 Jan 12;182:73–84. doi: 10.1016/j.biochi.2020.12.022

Fig. 4. Downregulation of MYC associated with inactivation of HSCs.

Fig. 4.

(A) Reduced expression of MYC was observed in the Oncopig fibrotic liver samples. (B) Diagram depicting upregulation of MYC due to chronic alcohol abuse resulting in hepatic apoptosis and activation and proliferation, which contributes to accelerated liver fibrosis. Adopted from Nevzorova et al. [37]. * denotes q-value = 9.5 × 10−4.