Methods	Design: Quasi‐experimental trial
	Setting: Ottawa, Canada
	Follow up: 24 months
	Recruitment: Invitation from participants' case manager
	Randomization: No randomization was performed
	Allocation: Not mentioned
	Blinding: Not mentioned
	Timing of outcome assessment: At baseline and every 6 months for 24 months
	Outcome assessor: Not mentioned
Participants	Population: Homeless individuals or people at risk of homelessness with problematic substance use
	Sample size: Total n=178, Intervention n=89, TAU n=89
Interventions	Intervention:
	A partnership between a community mental health agency and a programme located in a community health centre; each participant received a rent supplement and paid a maximum of 30% of their income towards rent; housing comprised private market rental units of participant's choice; participants also had access to opioid agonist treatment and substance use treatment.
	Comparator:
	Treatment as usual (TAU) including all social and health services available in the community other than the Housing First program. The services were scattered across a service rich city and included supportive housing, mental health, and substance use services available to people who are homeless as well as services that can be accessed while people are in a shelter.
Outcomes	Housing stability, mental health, quality of life, substance use
Notes