Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "A block randomized sequence was generated online by an investigator who was not involved in the recruitment of subjects"
Allocation concealment (selection bias)	Low risk	Quote: "A block randomized sequence was generated online by an investigator who was not involved in the recruitment of subjects"
Blinding of participants and personnel (performance bias)	Low risk	Quote: "The external appearance and the contents of the sachets of high dose, low dose, and placebo were identical looking.
Blinding of outcome assessment (detection bias)	Low risk	As the intervention was concealed properly, less likely that outcomes assessors were aware of the allocation
Incomplete outcome data (attrition bias)	Low risk	Minimal loss to follow up
Selective reporting (reporting bias)	Low risk	Authors seems to report all the relevant outcomes
Other bias	Low risk	No other risk of bias was noted