Methods
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Prospective randomized control trial conducted in Iran |
Participants
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Inclusion Criteria: "All premature newborns (n = 115) weighting 750–1500 g or <32 weeks' gestation who received antibiotics and total parenteral nutrition in NICU of Vali Asr Hospital were included" |
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Exclusion Criteria: "Premature babies <750 and more than 1500 g and neonates with congenital heart disease, congenital malformations, and immune system deficiency, even in their family members, were excluded from the study." |
Interventions
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Intervention: Multistrain powder probiotic infant formula containing Streptococcus thermophilus, Lactobacillus rhamnosus, Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium infantis, Lactobacillus casei. The dose was 0.8–1 g per day in 8–10 doses given for 13 days |
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Comparison: Enteral feed without probiotic |
Outcomes
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NEC |
Notes
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Data were taken from table 3 |