Methods | Prospective, randomized controlled trial conducted in Turkey |
Participants | Inclusion Criteria: preterm infants with a gestational age ≤32 week and a birth weight ≤ 1500 g |
Exclusion Crietria: "detected chromosomal abnormalities, previous gastrointestinal system surgery, a diagnosis of metabolic disease, babies lost in the first postnatal week and babies with severe sepsis episode were excluded from the study" | |
Interventions | Intervention: Probiotic supplementation: Lactobacillus rhamnosus (4.1×108 cfu) + Lactobacillus casei (8.2×108 cfu) + Lactobacillus plantorum (4.1×108 cfu) + Bifidobacterium animalis (4.1×108 cfu) |
Comparison: No probiotics | |
Outcomes | Mortality, NEC, sepsis |
Notes | Data were taken from table 2 |