Methods
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A multicenter, double‐blinded, randomized, placebo‐controlled trial conducted in Colombia |
Participants
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Inclusion Cciteria: "Preterm infants admitted to NICU, birth weight ≤ 2000 g, haemodynamically stable (blood pressure not requiring boluses or pressors), and ≤ 48 h of age" |
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Exclusion criteria: "Infants with evidence or suspicion of congenital intestinal obstruction or perforation, gastroschisis, large omphalocele, congenital diaphragmatic hernia, major congenital heart defects, or anticipated transfer to a NICU not participating in the study were excluded" |
Interventions
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Intervention: Probiotic administration:"Infants in the probiotic group received 5 drops of an oil‐based suspension containing 108 colony‐forming units of L reuteri DSM 17938" |
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Comparison: Oil based placebo |
Outcomes
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Mortality, NEC |
Notes
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Data were taken from table 2. The duration of the intervention was not clearly stated |