Random sequence generation (selection bias) |
Low risk |
Quote: "using sequential numbers generated at the computer center of…" |
Allocation concealment (selection bias) |
Low risk |
Quote: "The allocations were contained in opaque, sequentially numbered sealed envelopes" |
Blinding of participants and personnel (performance bias) |
Low risk |
Quote: "Thus, the only personnel who knew of the infants’ group assignments were the investigators and those in the breast‐milk team who were not involved in the care of the study infants" |
Blinding of outcome assessment (detection bias) |
Low risk |
Quote: "Whenever an infant was suspected to have NEC, the infant was evaluated by two senior‐attending neonatologists who did not know the group assignment of the infant" |
Incomplete outcome data (attrition bias) |
Low risk |
Minimal loss to follow up |
Selective reporting (reporting bias) |
Low risk |
Authors seem to report all the outcomes irrespective of their statistical significance |
Other bias |
Low risk |
No other risk of bias was noted |