Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "After a random start, wards were systematically assigned, blocked on VDAs, for infants to receive…"
		Comment: Most likely done
Allocation concealment (selection bias)	Low risk	Quote: "…from gelatinous capsules of identical appearance"
		Comment: Most likely done
Blinding of participants and personnel (performance bias)	Low risk	Quote: "The protocol and procedures for the trial were reviewed and approved by the Nepal Medical Research Council, Kathmandu, and the Joint Committee on Clinical Investigation at the Johns Hopkins University School of Medicine, Baltimore"
		Comment: Most likely done.
Blinding of outcome assessment (detection bias)	Unclear risk	Quote: "Verbal autopsy reports were independently reviewed by two physicians (SKK and RA) who standardized their reviews for ‘S0 pre‐study death reports"
		Comment: Most likely done
Incomplete outcome data (attrition bias)	Unclear risk	Total number of loss to follow up: n (%)
		The loss to follow up was not balanced
Selective reporting (reporting bias)	Low risk	Authors seem to report all the outcomes irrespective of their statistical significance
Other bias	Unclear risk	No other risk of bias was noted