Methods
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A prospective, randomized, case‐controlled trial conducted in China |
Participants
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Inclusion criteria: "hospital‐born formula‐fed infants with a gestational age of 30–37 weeks and a birth weight between 1500 and 2500 g" |
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Exclusion criteria: "severe neonatal pathologies, such as severe birth complications, GI malformations, chromosomal abnormalities, known immunodeficiency, hydrops fetalis, central venous catheter, antifungal drugs, and probiotics" |
Interventions
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Intervention: "The intervention group received Saccharomyces boulardii CNCM I‐745, administered two times per day as separate medication, not mixed with formula, at a dosage of 50 mg/kg. The study period ended at the 28th day after birth or when the infant was discharged from the hospital. Minimum duration of intervention was 7 days" |
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Control: "Nothing was administered to the control group" |
Outcomes
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Neonatal sepsis |
Notes
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Data were taken from table 2 |