Skip to main content
. 2021 Mar 5;17(1):e1141. doi: 10.1002/cl2.1141
Methods A prospective, randomized, case‐controlled trial conducted in China
Participants Inclusion criteria: "hospital‐born formula‐fed infants with a gestational age of 30–37 weeks and a birth weight between 1500 and 2500 g"
Exclusion criteria: "severe neonatal pathologies, such as severe birth complications, GI malformations, chromosomal abnormalities, known immunodeficiency, hydrops fetalis, central venous catheter, antifungal drugs, and probiotics"
Interventions Intervention: "The intervention group received Saccharomyces boulardii CNCM I‐745, administered two times per day as separate medication, not mixed with formula, at a dosage of 50 mg/kg. The study period ended at the 28th day after birth or when the infant was discharged from the hospital. Minimum duration of intervention was 7 days"
Control: "Nothing was administered to the control group"
Outcomes Neonatal sepsis
Notes Data were taken from table 2