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. 2020 May 18;16(2):e1085. doi: 10.1002/cl2.1085
Methods Design: RCT
Unit of randomisation: Indivdually randomised trial
Participants Location/Setting: Schools in urban Beijing, China
Sample size: 757 adolescent girls
Dropouts/withdrawals: 59/757 loss to follow‐up
Sex: Only adolescent girls
Mean age: 10 (0.03) years
Inclusion criteria: Healthy girls aged 10 years
Exclusion criteria: Not specified
Interventions Intervention (sample size):
Group 1 (N = 238): Girls consumed a carton of 330 ml milk fortified with Ca on school days over the study period
Group 2 (N = 260): Girls received the same quantity of milk additionally fortified with 5 or 8 mg cholecalciferol
The duration of intervention was 24 months
Control (sample size):
Group 3 (N = 259): Control girls did not receive any intervention
Outcomes Primary outcomes: Nutrient intake, bone mineral content, bone mineral density, serum PTH, serum calcium, height, weight and vitamin D levels
Secondary outcomes: Not specified
Timing of outcome assessment: Immediately after the 24 months of intervention and 3 years post intervention
Notes Study start date: April 1999
Study end date: March 2001
Funding source: Australian Dairy Research and Development Corporation, Murray Goulburn Co‐operative Co. Limited (formulated and produced the milk supplements) and the Nestle' Foundation provided financial support for the laboratory analyses
Conflicts of interest: None declared