| Review article | Target population | Intervention reviewed | HIC or LIC | Last search date | Primary outcomes | Secondary outcomes | No. of studies | Sub group analysis | Quality assessment |
Meta‐analysis MD (95% CI) |
|---|---|---|---|---|---|---|---|---|---|---|
| Salam Rehana et al. (2016) | Adolescents (11–19 years) and Youth (15–24 years) | Micronutrient supplementation | Global | December 2014 | Outcomes were not prespecified so all the outcomes reported by the study authors were included | Outcomes were not prespecified | 31 | School setting | Cochrane risk of bias assessment tool | Impact of Iron‐folic acid supplementation on anaemia RR = 0.69(0.62, 0.76) |
| Salam Rehana et al. (2016) | Pregnant Adolescents | Micronutrient supplementation | Global | December 2014 | Outcomes were not prespecified so all the outcomes reported by the study authors were included | Outcomes were not prespecified | 16 | Not mentioned | Cochrane risk of bias assessment tool | Impact of nutrition interventions on |
| Nutritional education | Mean birth weight SMD = 0.25(0.08,0.41) | |||||||||
| Low birth weight RR = 0.70(0.57, 0.84) | ||||||||||
| Lassi Zohra et al. (2017) | Adolescents (10–19 years) and Women of reproductive age | Micronutrient supplementation | Global | October 2016 | Mortality, pregnancy outcomes, morbidity, nutritional, anthropometrics | 107 | Family based interventions | GRADE Working Group grades of evidence | Iron supplementation vs. placebo: | |
| Food/protein energy supplementation | ||||||||||
| Nutrition education for pregnant adolescents | Hemoglobin concentration (g/L) in adolescents: SMD = 1.83(0.59, 3.08) | |||||||||
| Obesity prevention | IFA supplementation vs. placebo: | |||||||||
| Hemoglobin (g/L) in adolescents: MD = 2.24(0.36, 4.12) | ||||||||||
| Management of gestational diabetes | Vitamin D supplementation vs. placebo | |||||||||
| 25(OH)D (nmol/L) concentration in adolescents: MD = 8.80(−2.68, 20.28) | ||||||||||
| Zinc supplementation vs. placebo: | ||||||||||
| Hemoglobin (g/L) concentration in adolescents: SMD = 4.81(0.97, 8.66) | ||||||||||
| Serum zinc (mol/L) in adolescents: SMD = 4.28(2.49, 6.06) | ||||||||||
| Preterm birth in pregnant adolescents: RR = 0.57(0.46, 0.69) | ||||||||||
| Low birth weight in pregnant adolescents: RR = 0.39(0.15, 0.98) | ||||||||||
| Iodine supplementation vs. placebo: | ||||||||||
| TSH (U/dL) concentration in adolescents:.SMD = 0.25(−0.02, 0.52) | ||||||||||
| Interventions for prevention of obesity in pregnant adolescent: birth weight: SMD = −0.05(−0.11, 0.01) | ||||||||||
| Interventions for management of obesity in adolescents: BMI: | ||||||||||
| SMD = −0.24(−0.36, −0.13) | ||||||||||
| Hoyland, Dye and Lawton (2009) | Children or adolescent (aged 18 years) | Any type of breakfast manipulation | Global | January 2009 | Outcome measures of cognitive performance | 45 | Not mentioned | JADAD criteria used | Not performed | |
| Meiklejohn, Ryan and Palermo (2016) | Adolescents aged 18 years | Nutrition education was delivered in conjunction with complementary strategies | High and Middle Income Countries | September 2014 | Anthropometric measures, biochemical markers, dietary consumption data, changes in dietary intake of fruits and vegetables, snack foods, fat, sucrose, sugar‐sweetened beverages and soft drinks | 13 | Not mentioned | American Dietetics Association. ADA | Not performed | |
| Evidence Analysis Manual, IV ed | ||||||||||
| Das et al. (2013) | Children and adolescent till age of 18 years and women of reproductive age | Fortification | Global | November 2012 | Serum micronutrient levels, hematologic markers, anthropometric indicators, pregnancy outcomes, morbidity outcomes, mortality | 201 | Age groupsCountries | GRADE Working Group grades of evidence | Results for iron fortification in children | |
| Hemoglobin levels: SMD = 0.55 (0.34, 0.76) | ||||||||||
| Population characteristics | Effect on anaemia: RR = 0.55 (0.42, 0.72) | |||||||||
| Type of food fortified | Results for zinc fortification in children | |||||||||
| Duration of intervention | Serum zinc levels: SMD = 1.28 (0.56, 2.01) | |||||||||
| Hemoglobin level: SMD = −0.11(−0.52, 0.31) | ||||||||||
| Copper Levels: SMD = 0.57 (−0.91, 2.06) | ||||||||||
| Serum alkaline phosphatase levels: SMD = 0.94(−0.29, 2.17) | ||||||||||
| Weight gain: SMD = 0.50(−0.12, 1.11) | ||||||||||
| Height growth: SMD = 0.52 (0.01, 1.04) | ||||||||||
| Calcium and vitamin D fortification | ||||||||||
| Serum parathyroid hormone levels:SMD = −0.40 (−0.56,−0.24) | ||||||||||
| Serum vitamin D levels: SMD = 1.23 (0.35,2.11) | ||||||||||
| Serum calcium levels:SMD = −0.40 (−0.59,−0.20) | ||||||||||
| Results for multiple micronutrient fortification in children | ||||||||||
| Hemoglobin levels: SMD = 0.75(0.41, 1.08) | ||||||||||
| Effect on anaemia: RR: 0.55 (0.42, 0.71) | ||||||||||
| Effect on vitamin A deficiency: RR = 0.90 (0.76, 1.06) | ||||||||||
| Height‐for age Z‐score: SMD: 0.13(−0.04, 0.29) | ||||||||||
| Weight‐for age Z‐score: SMD: −0.12(−0.43, 0.20) | ||||||||||
| Weight‐for height Zscore:SMD: −0.11(−0.40, 0.17) | ||||||||||
| Results for iron, folate and calcium/vitamin D fortification in women | ||||||||||
| Hemoglobin levels: SMD: 0.62 (0.36,0.89) | ||||||||||
| Effect on anaemia: RR: 0.68 (0.49, 0.93) | ||||||||||
| Marquez, Racey, Preyde, Hendrie and Newton (2015) | Adolescents aged 12 to 18 years | Interventions targeting an increase in dairy food or Calcium intake | Global | February 2015 | Intakes of calcium, milk and dairy per day | 16 | Not mentioned | The Quality | Not performed | |
| Assessment Tool for Quantitative Studies | ||||||||||
| by EPHPP | ||||||||||
| Samuelson 2017 | Adolescents aged 10–19 years | Diet and nutrition interventions | Global | January 2016 | Depression | 11 | Not mentioned | Not mentioned | Not performed | |
| Lohner et al. (2012) | Children and adolescents | Folate supplementation | Global | March 2009 | Serum folate content, erythrocyte folate content | 26 | Not mentioned | Not mentioned | Not performed |