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. 2020 May 18;16(2):e1085. doi: 10.1002/cl2.1085
Methods Design: RCT
Unit of randomisation: Individually randomised trial
Participants Location/Setting: A secondary girls school in Pune City, Maharashtra, India
Sample size: 180 apparently healthy adolescent girls
Dropouts/withdrawals: 8 loss to follow‐up of 180
Sex: Adolescent girls only
Mean age: 12.5 (0.85) years
Inclusion criteria: Apaarently healthy adolescent girls
Exclusion criteria: Girls who were ill or had in the recent past any illness such as fever, respiratory or gastrointestinal infection, or those undergoing medical treatment, or taking multivitamin mineral supplements were identified and excluded from the study
Interventions Intervention (sample size):
Intervention group 1 (N = 60)
Supplement was provided in the form of six different snacks to each girl with one snack (average amount 100 g/serving) per day for 6 school days in a week. The average zinc content of the food supplements was 2.2 ± 0.4 mg/serving
Intervention group 2 (N = 59)
The ayurvedic zinc tablet containing 20 mg of jasad bhasma, equivalent to 16.6 mg of elemental zinc, was given to each girl every day for 6 school days/week under the guidance of an ayurvedic doctor
The intervention was provided for a duration of 10 weeks
Control (sample size):
Control group (N = 53)
No supplements given to control
Outcomes Primary outcomes: Dietry intake, haemoglobin levels, plasma zinc, plasma beta‐carotene, plasma retinol, plasma vitamin C
Secondary outcomes: Not specified
Timing of outcome assessment: After 10 weeks of intervention
Notes Study start date: Not specified
Study end date: Not specified
Funding source: Zensar Foundation, Pune, India
Conflicts of interest: Not specified