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. 2020 May 18;16(2):e1085. doi: 10.1002/cl2.1085
Methods Design: RCT
Unit of randomisation: Individually randomised trial
Participants Location/Setting: School in the Galle district, Sri Lanka
Sample size: 821 school children
Dropouts/withdrawals: 47 out of 821 loss to follow‐up
Sex: Both male and female children were enrolled
Mean age: 13.5 years
Inclusion criteria: Children with Hb level >80 g/L were eligible for the study
Exclusion criteria: Children suffering from acute or chronic diseases, inflammatory conditions, giving a history of any drug consumption other than paracetamol or antihistamines for minor ailments, currently consuming nutrient supplements or having donated blood or received a blood transfusion within the last 4 months were excluded from the study
Interventions Intervention (sample size):
Children were supplemented with two capsules per day containing either:
Group 1: Iron (50 mg/day) in the form of ferrous fumarate (N = 202)
Group 2: Zinc (14 mg/day) in the form of zinc sulphate (N = 213)
Group 3: Combined (iron + zinc) (N = 216)
Control (sample size):
Group 4: Placebo made of anhydrous lactose (N = 190)
Intervention was provided on school days for a duration of 24 weeks
Outcomes Primary outcomes: Height, weight, BMI, height‐for‐age, weight‐for‐age, stunted, underweight, haemoglobin, serum zinc, serum ferritin
Secondary outcomes: Not specified
Timing of outcome assessment: After 24 weeks of intervention
Notes Study start date: Not specified
Study end date: Not specified
Funding source: International Atomic Energy Agency (IAEA‐SRL‐11958)
Conflicts of interest: Not specified