Table 6.
Comparison of the original analysis plan and actual model employed
| Planned analysis | Actual analysis | |
|---|---|---|
| Outcomes | Maternal anaemia at term | Maternal anaemia at term (Hb < 109 g/l) |
| Maternal infection intensity | Trichiura intensity (none vs. any (light/moderate/heavy) intensity) | |
| Maternal haemoglobin at term | Hookworm intensity (none vs. any (light/moderate/heavy) intensity) | |
| Maternal ferritin | ||
| Maternal anthropometric measures | LBW (<2500 g) | |
| Preterm birth (<37 weeks of gestation) | ||
| Maternal BMI | ||
| Birth weight | ||
| Low birth weight | ||
| Preterm birth | ||
| Perinatal mortality | ||
| Stillbirth | ||
| Congenital abnormalities | ||
| Infant Mortality | ||
| Covariates | Schistosoma intensity | Hookworm intensity (none vs. any (light/moderate/heavy) intensity) |
| Ascaris intensity | Trichiura intensity (none vs. any (light/moderate/heavy) intensity) | |
| Hookworm intensity | Haemoglobin (Hb < 109 g/l) | |
| Trichuria intensity | ||
| Haemoglobin | ||
| BMI | ||
| Socio‐economic status | ||
| Deworming drug | ||
| WASH practices | ||
| Population level worm intensities | ||
| Effect Modifiers | BMI (<18.5 kg/m2, 18.5 to 25 kg/m2) | BMI (<18.5 kg/m2, 18.5 to 25 kg/m2) |
| Anaemia status (none, mild, moderate, severe) | Aanemia (Hb<109 g/l) | |
| Schistosoma intensity (light, moderate, heavy) | Trichiura intensity (none vs. any (light/moderate/heavy) intensity) | |
| Ascaris intensity (light, moderate, heavy) | ||
| Hookworm intensity (light, moderate, heavy) | ||
| Trichuria intensity (light, moderate, heavy) | ||
| Any STH or Schistosoma infection (light, moderate, heavy) | ||
| Concomitant interventions |