. 2019 Sep 24;15(3):e1052. doi: 10.1002/cl2.1052

Table 13.

Summary of findings table

Mass deworming for STH and Schsitosomisis during pregnancy compared to placebo
Population: Pregnant women
Setting: Low‐ middle‐ income countries of Uganda, Tanzania and Philippnes
Intervention: Mass deworming with any drug
Comparison: Placebo
		Aggregate evidence		IPD evidence
Outcomes	No of Participants (Studies)	RR (95% CI)	Quality of the evidence (GRADE)	RR (95% CI)	Quality of the evidence (GRADE)
Maternal Anaemia	5216	0.94 (0.89–0.99)	⊕⊕⊕⊝	0.77 (0.73‐0.81)	⊕⊕⊕⊝
Maternal Anaemia	(3 studies)	0.94 (0.89–0.99)	Moderate ^a	0.77 (0.73‐0.81)	Moderate ^a
Maternal T.Trichiura intensity	2867	1.06 (0.87, 1.30)	⊕⊕⊕⊝	0.69 (0.42‐1.13)	⊕⊕⊕⊝
Maternal T.Trichiura intensity	(2 studies)	1.06 (0.87, 1.30)	Moderate ^a	0.69 (0.42‐1.13)	Moderate ^a
Maternal hookworm intensity	2867	0.39 (0.04, 3.93)	⊕⊕⊕⊝	0.52 (0.18‐1.47)	⊕⊕⊕⊝
Maternal hookworm intensity	(2 studies)	0.39 (0.04, 3.93)	Moderate ^a	0.52 (0.18‐1.47)	Moderate ^a
LBW	2267	1.04 (0.79, 1.38)	⊕⊕⊕⊝	0.89 (0.67, 1.18)	⊕⊕⊕⊝
LBW	(2 studies)	1.04 (0.79, 1.38)	Moderate ^a	0.89 (0.67, 1.18)	Moderate ^a
Preterm birth	2707	0.84 (0.51, 1.39)	⊕⊕⊕⊝	0.69 (0.47, 1.03)	⊕⊕⊕⊝
Preterm birth	(2 studies)	0.84 (0.51, 1.39)	Moderate ^a	0.69 (0.47, 1.03)	Moderate ^a

Abbreviations: CI, confidemce interval; LBW, low birthweight; RR, risk ratio; STH, soil transmitted helminths.

GRADE Working Group grades of evidence.

High quality: Further research is very unlikely to change our confidence in the estimate of effect.

Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.

Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.

Very low quality: We are very uncertain about the estimate.

^{^a}

Downgraded for study limitations ‐ obtained only a selected sample of IPD.