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. 2021 Mar;21(1):82–95. doi: 10.4314/ahs.v21i1.13

Table S2.

Subgroup analysis for FPG of various variables

Group Number of studies WMD (95% CI) P for heterogeneity I2 %
Total 7 -0.19 [-0.42, 0.05] < 0.001 93.00
PG 94.00
NGR 4 -0.33 [-0.95, 0.29] < 0.001 93.70
IGT or DM 3 -0.12 [-0.42, 0.19] < 0.001 91.20
Dosage
Allopurinol ≥ 300 mg/d 3 -0.53 [-0.74, -0.32] 0.217 34.60
Allopurinol < 300 mg/d 2 0.10 [0.07, 0.13] 0.688 0
Benzbromarone 50 mg/d 1 -0.33 [-0.56, -0.10] - -
Adjust according to SUA 1 0.01 [-0.11, 0.13] - -
Mean SUA at baseline
≥ 420 umol/L 4 -0.17 [-0.61, 0.27] < 0.001 92.00
< 420 umol/L 3 -0.20 [-0.58, 0.18] < 0.001 94.00
Reduction of SUA
≥ 150 umol/L 3 -0.29 [-0.99, 0.41] < 0.001 96.00
< 150 umol/L 4 -0.13 [-0.38, 0.11] < 0.001 85.00
Mean age
≥ 50 years 5 -0.13 [-0.34, 0.07] < 0.001 88.80
< 50 years 2 -0.26 [-1.07, 0.56] < 0.001 94.10
BMI
≥ 28 3 -0.15 [-0.62, 0.31] < 0.001 91.00
< 28 3 -0.05 [-0.29, 0.20] < 0.001 99.00
Duration
≥ 6 months 3 -0.33 [-0.95, 0.29] < 0.001 93.70
< 6 months 4. -0.12 [-0.42, 0.19] < 0.001 91.20
Number of participant
>60 4 -0.07 [-0.28, 0.13] < 0.001 87.10
≤60 3 -0.29 [-0.72, 0.14] < 0.001 88.60

Abbreviations: PG, plasma glucose; NGR, normal glucose regulation; IGT, impaired glucose tolerance; DM, diabetes mellitus; SUA, serum uric acid; BMI, body mass index.