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. 2019 Feb 12;11(8):885–900. doi: 10.4155/fmc-2018-0404

Figure 3. . tRNA methyltransferase activity in cancer cells.

Figure 3. 

tRNA methyltransferase enzymes catalyze specific chemical modifications on tRNAs to direct translational programs that are either tumor suppressive (unfilled) or oncogeneic (filled) in cancer cells.

CBT: Codon-biased translation; tRF: Small tRNA-derived fragment.