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Docking results of 6-hydroxy-3, 4 - dihydronaphthalen-1- on chalcone - like derivatives having anti-tyrosinase activity, and kojic acid into the mushroom tyrosinase active site.
| Compounds | ΔG (kcal/mol) | Ki (μM) |
|---|---|---|
| C1 | -6.35 | 18.83 |
| C2 | -7.46 | 3.38 |
| C3 | -7.28 | 3.86 |
| C4 | -6.35 | 21.98 |
| C5 | -6.39 | 20.83 |
| C6 | -6.40 | 20.35 |
| C7 | -6.78 | 10.70 |
| C8 | -7.44 | 3.49 |
| C9 | -6.17 | 30.14 |
| C10 | -6.50 | 17.20 |
| Tropolone | -4.36 | 0.61 × 103 |
| Kojic acid | -3.57 | 2.40 × 103 |
