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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Spine J. 2021 Mar 5;21(7):1205–1216. doi: 10.1016/j.spinee.2021.03.002

Figure 6. BMP-2 and pSMAD1/5/8 expression correlate with Pfirrmann MRI grades.

Figure 6.

Figure 6.

Figure 6.

Figure 6.

(a) Pfirrmann grade 3 and grade 4 discs had significantly higher BMP-2 expression as compared to Pfirrmann grade 2 discs. (b) Pfirrmann grade 4 discs had significantly higher pSMAD1/5/8 expression as compared to Pfirrmann grade 2 discs. (c) No significant differences in ALK3 expression were observed across the Pfirrmann grades. (d) No significant differences in MMP-13 expression were observed across the Pfirrmann grades.