Table 3.
Demographic and clinical features of the severe COVID-19 cases.
| Variable | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 |
|---|---|---|---|---|---|---|---|
| Age (year) | 35 | 24 | 27 | 31 | 30 | 36 | 41 |
| Gravidity | 2 | 2 | 1 | 4 | 1 | 3 | 6 |
| Gestational week | 31 | 33 | 38 | 34 | 28 | 32 | 12 |
| Pre-pregnancy BMI (kg/m2) | 20 | 28 | 31 | 26 | 25 | 30 | 28 |
| 25-OH D vitamin (ng/mL) | 6 | 4.5 | 10.9 | 8 | 12 | 9.1 | 10.6 |
| D vitamin supplementation | – | – | – | – | – | – | – |
| Calcium (mg/dL) | 8 | 7.5 | 7.4 | 8 | 8.30 | 7.8 | 7.6 |
| Alkaline phosphatase (U/L) | 150 | 103 | 61 | 42 | 96 | 214 | 32 |
| Total protein (g/L) | 56 | 51 | 54 | 48 | 55 | 47 | 48 |
| D-dimer | 1.46 | 1.65 | 15.4 | 2.1 | 0.92 | 3.86 | 0.9 |
| CRP | 127.9 | 38 | 167.7 | 181.5 | 100.5 | 186.8 | 87.1 |
| IL-6 | 101 | 8.6 | 75.5 | 701 | 33.3 | 135 | 146 |
| ICU admission | + | + | + | + | + | + | + |
| High flow oxygen | + | + | + | + | + | + | + |
| Mechanical ventilation | – | – | + | + | + | + | + |
| Maternal outcome | Discharged healthily at 30 weeks | Maternal ex | Maternal ex | Maternal ex | Maternal ex | Maternal ex | |
| Birth weight (g) | NA | 1870 | NA | NA | 1720 | 2050 | – |
| APGAR 1st and 5th min | NA | 7/9 | NA | NA | 5/7 | 7/9 | – |
| NICU | NA | + | + | NA | + | + | – |
| Neonatal complication | NA | LBW | LBW, RDS | NA | LBW, RDS | LBW | abortion |
| Nasopharyngeal PCR of the newborn | NA | – | – | NA | – | – | – |
| Neonatal outcome | NA | Discharged healthily on 18 days of life | Discharged healthily on 12 days of life | NA | Discharged healthily on the 88 days of life | Discharged healthily on the 24 days of life | abortion |
ICU: intensive care unit.
NICU: neonatal intensive care unit admission.
LBW: low birth weight.
RDS: Respiratory distress syndrome.
NA: Not applicable.