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. 2021 Jul 16;12(31):10655–10663. doi: 10.1039/d1sc02760c

The redox-active amino acids of Hb. Hb surface-exposed residues (in tetramer or dimer form) are in bold font. Histidine residues in random coil regions are marked with (*).

Redox-active amino acids α-Chain β-Chain
Cys (C) C92
Tyr (Y) Y24, Y42, Y140 Y34, Y144
Trp (W) W14 W14, W36
His (H) H20*, H45*, H50*, H58, H72*, H87, H89*, H103, H112*, H122 H62, H76*, H91, H96*, H145, H142