TABLE 3.
Volume (mm3) of subcortical nuclei calculated from the manual segmentation and co‐registered atlases
| Name | Manual annotation | HybraPD | PD25 | CIT168 | CerebrA | AAL3 |
|---|---|---|---|---|---|---|
| Pu | 4,338.6 ± 503.7 | 4,223.1 ± 495.7 | 4,842.0 ± 565.9 | 5,365.1 ± 631.4 | 4,620.1 ± 550.1 | 6,166.6 ± 685.1 |
| CN | 4,166.9 ± 468.3 | 4,018.0 ± 574.5 | 3,665.2 ± 496.8 | 5,000.0 ± 690.7 | 4,129.0 ± 595.3 | 5,441.5 ± 1,036.7 |
| NAC | 286.1 ± 22.1 | 273.8 ± 22.4 | # | 384.8 ± 32.1 | 356.8 ± 36.2 | 856.9 ± 89.1 |
| VeP | 142.9 ± 12.0 | 142.7 ± 13.1 | # | 93.4 ± 9.2 | # | # |
| GPe | 1,209.3 ± 155.6 | 1,194.4 ± 150.6 | 1,085.6 ± 133.2 | 790.6 ± 103.0 | # | # |
| GPi | 506.6 ± 66.1 | 488.7 ± 62.6 | 438.4 ± 47.5 | 372.8 ± 47.0 | # | # |
| SNr | 285.8 ± 27.1 | 272.0 ± 31.8 | # | 273.9 ± 30.6 | # | 287.9 ± 31.1 |
| SNc | 212.8 ± 21.9 | 209.7 ± 22.1 | # | 127.2 ± 14.8 | # | 176.8 ± 21.0 |
| RN | 290.9 ± 39.3 | 278.5 ± 33.7 | 191.5 ± 21.2 | 277.9 ± 31.4 | # | 321.4 ± 34.5 |
| STN | 144.4 ± 19.7 | 149.0 ± 18.4 | 67.0 ± 8.8 | 120.3 ± 16.0 | # | # |
| HN | 77.6 ± 10.9 | 78.1 ± 8.9 | # | 50.6 ± 5.4 | # | # |
| Thal | 5,888.1 ± 452.7 | 5,659.4 ± 530.3 | 5,439.3 ± 460.8 | # | 6,798.2 ± 556.9 | 6,002.7 ± 578.2 |
Note: “#” denotes the ROI of that row is not labeled in the atlas of the corresponding column.
Abbreviations: CN, caudate nucleus; GPe and GPi, external and internal globus pallidus; HN, habenular nuclei; NAC, nucleus accumbens; Pu, putamen; RN, red nucleus; SNr and SNc, pars reticulata and pars compacta of substantia nigra; STN, subthalamic nucleus; Thal, thalamus; VeP, ventral pallidum.