Fig 6. Maternal-Fetal Interface Viral Loads.

All tissue samples were tested for the presence of viral RNA using ZIKV-specific QRT-PCR. A. All tissues >0.1 copy vRNA/mg tissue are shown above; only tissues with viral loads greater than the theoretical limit of quantification (3 copies vRNA/mg) were used for statistical analysis. A Mann-Whitney U test was used to assess statistically significant differences between the experimental groups (**p<0.01). B-E. Pearson correlation analysis was performed to assess correlation between the percent of tissues collected that were vRNA positive and the duration (B and C), peak (D), and area under the curve (E) of viremia.