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. 2021 Jul 28;12:696059. doi: 10.3389/fpsyt.2021.696059

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Copyright © 2021 Okamoto, Natsuyama, Igata, Konishi, Tesen, Ikenouchi and Yoshimura.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between serum IL-6 levels and serum QA levels in the healthy control group. A positive correlation was found between the serum IL-6 levels and the serum QA levels (r = 0.78, p = 0.010) in the healthy control group. Relative Area: The peak areas of the metabolites were normalized against those of the internal standards, and the resultant relative areas were further normalized by the sample amount explained in the Measurement of metabolites of the Kyn pathway. Thus, serum QA levels demonstrated as the ratio comparing with internal standard.