Table 4A.

Relationship between metabolites of the Kyn pathway and cytokines, hsCRP, and BDNF in the schizophrenia group.

	IL-6	TNF-α	hsCRP	BDNF
Trp	0.028	−0.092	0.33	0.087
	(p = 0.89)	(p = 0. 63)	(p = 0.080)	(p = 0.65)
Kyn	0.3	0.53	0.36	−0.21
	(p = 0.11)	(p = 0.0026)	(p = 0.051)	(p = 0.26)
3-HK	0.24	0.29	0.25	−0.21
	(p = 0.21)	(p = 0.13)	(p = 0.18)	(p = 0.28)
QA	0.42	0.34	0.27	−0.23
	(p = 0.059)	(p = 0.12)	(p = 0.24)	(p = 0.31)
5-HT	−0.3	−0.032	−0.23	0.49
	(p = 0.13)	(p = 0.87)	(p = 0.23)	(p = 0.0061)
Kyn/Trp	0.27	0.67	0.18	−0.26
	(p = 0.16)	(p = 0.000046)	(p = 0.36)	(p = 0.16)
5-HT/Kyn	−0.34	0.1	−0.24	0.55
	(p = 0.069)	(p = 0.60)	(p = 0.22)	(p = 0.0018)
3-HK/Kyn	0.063	0.015	0.1	−0.12
	(p = 0.75)	(p = 0.93)	(p = 0.60)	(p = 0.52)
QA/Kyn	0.32	0.25	0.16	0.0085
	(p = 0.16)	(p = 0.27)	(p = 0.50)	(p = 0.97)