Fig 8. Cholinergic modulation of neuron frequency-current relationship.
A, Frequency-current (f-I) curve of the cortical neuron model with different gKs values simulating different levels of ACh neuromodulation (gKs = 0 mS/cm2 for high ACh modulation and gKs = 1.5 mS/cm2 for no ACh neuromodulation). B, Spike-Frequency-Adaptation (SFA) showed by the voltage traces of different gKs values with current of 1.5μA/cm2 being applied (Same color code with A).