Table 4.
Peripheral blood micronucleus assay results for male rats exposed to 5-AT.
| Controls | 5-AT mg/kg-day | ||||||
|---|---|---|---|---|---|---|---|
| untreated | EMS | 0 | 177 | 313 | 623 | ||
| %-RET | Mean | 3.842 a | 1.15 c | 2.577 b | 2.795 b | 2.927 b | 2.933 b |
| S.D.* | 0.646 | 0.26 | 0.476 | 0.673 | 0.457 | 0.344 | |
| %MN-RET | Mean | 0.118 d | 1.053 e | 0.1 d | 0.09 d | 0.105 d | 0.118 d |
| S.D.* | 0.026 | 0.204 | 0.017 | 0.021 | 0.042 | 0.042 | |
N= 6; % RET:
- statistically significant difference from b and c;
- no statistical difference between dose groups;
-statistically significant difference from a and b;
% MN-RET:
- no statistically significant difference between groups;
-statistically significant difference (p<0.001) from d.