Table 2b.
Area under the curve and unstandardized beta coefficients for density and dichotomous FH measures from logistic and linear regression models for each of the alcohol variables, across all subjects.
| FH Measures | Diagnostic Accuracy | Likelihood of AUD | Age of onset Regular Drinking | P3 Amplitude | |||||
|---|---|---|---|---|---|---|---|---|---|
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| N | AUC | N | b | OR | N | b | N | b | |
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| Density Measures | |||||||||
| FHDrPSND–AUDDx | 9,805 | 0.64* | 9,684 | 2.21* | 9.13 | 7,749 | −2.23* | 5,254 | −1.95* |
| FHDrPSND–AUDMaxSxCnt | 9,805 | 0.65* | 9,684 | 3.01* | 20.45 | 7,749 | −3.05* | 5,254 | −2.52* |
| FHDrAR–AUDDx | 14,566 | 0.62* | 14,264 | 2.04* | 7.71 | 11,456 | −2.28* | 6,894 | −1.64* |
| FHDrAR– AUDMaxSxCnt | 14,566 | 0.62* | 14,264 | 2.85* | 17.45 | 11,456 | −2.98* | 6,894 | −2.12* |
| Dichotomous Measures | |||||||||
| FHFather–AUDDx | 6,752 | 0.54* | 6,696 | 0.58* | 1.80 | 5,505 | −0.74* | 3,656 | −1.05* |
| FHMother–AUDDx | 9,593 | 0.52* | 9,436 | 0.53* | 1.71 | 7,607 | −0.47* | 5,106 | −0.81* |
| FHParent–AUDDx | 10,411 | 0.54* | 10,231 | 0.60* | 1.83 | 8,220 | −0.55* | 5,499 | −0.94* |
| FHFirst–AUDDx | 12,164 | 0.55* | 11,340 | 0.69* | 2.00 | 9,184 | −0.78* | 6,157 | −0.59 |
AUC=area under curve. OR=Odds Ratio.
p<0.006 (Bonferroni corrected).