Table 1.
Demographics, preoperative laboratory results, NLR and PLR values, and operative data.
| Demographics | Non-AKI (n=310) | AKI (n=86) | P-value |
|---|---|---|---|
| Age (years) (mean±SD) | 60.6±8.8 | 63±8.6 | 0.014 |
| Sex, male, n (%) | 243 (78) | 69 (80) | 0.767 |
| Weight, kg | 78.9±16 | 79.1±14 | 0.881 |
| BMI, kg/m2 | 27,7±4.4 | 28.1±4.6 | 0.475 |
| Diabetes mellitus, n (%) | 95 (30.6) | 31 (34.8) | 0.512 |
| Hypertension, n (%) | 199 (64.1) | 58 (67.4) | 0.724 |
| Smoking, n (%) | 122 (39.3) | 38 (44.1) | 0.641 |
| Hyperlipidemia, n (%) | 138 (42.3) | 33 (37.5) | 0.475 |
| Preoperative EF, % | 58.3±9 | 56±10 | 0.153 |
| Postoperative EF, % | 57±8 | 57±10 | 0.910 |
| History of atrial fibrillation, n (%) | 129 (41.6) | 29 (33.7) | 0.591 |
| History of CVA, n (%) | 11 (356) | 5 (5,8) | 0.432 |
| History of MI, n (%) | 69 (22,2) | 21 (24,4) | 0.332 |
| Preoperative measurements | |||
| Creatinine, mg/dl | 0,88±0,18 | 0,99±0,28 | < 0.001 |
| BUN | 16.8±6.1 | 20.8±7.7 | 0.002 |
| Albumin | 3.8±0.4 | 3.7±0.4 | 0.016 |
| Total cholesterol | 128 (80-404) | 126 (70-319) | 0.936 |
| LDL | 128±36,8 | 118±42,6 | 0.359 |
| Triglyceride | 123 (40-675) | 128 (31-441) | 0.636 |
| CRP | 8.1 (0.2-145) | 9.5 (1.7-95) | 0.446 |
| Hemoglobin (mg/dl) | 13.7±1 | 13.6±1.2 | 0.311 |
| Leukocyte count (´ 103/µL) | 8.55±2.58 | 8.06±2.36 | 0.078 |
| Neutrophil (´ 103/µL) | 5.36±1.85 | 5.41±1.88 | 0.81 |
| Lymphocyte (´ 103/µL) | 2.32±0.79 | 1.84±0.77 | < 0.001 |
| Platelet (´ 103/µL) | 224.92±62.42 | 238.40±72.58 | 0.088 |
| NLR | 2.51±0.85 | 3.32±1.15 | < 0.001 |
| PLR | 107.51±31.25 | 154.99±43.6 | < 0.001 |
| Operative data | |||
| Cross-clamping time (min) | 62±19 | 60±21 | 0.301 |
| CPB time (min) | 109±29 | 107±33 | 0.729 |
| CABG 1-3 (%) | 138 (44.5) | 42 (48.8) | |
| CABG > 3 (%) | 172 (55.5) | 44 (51.2) | |
| In-hospital mortality, n (%) | 5 (1.61) | 1 (1.47) | 1.000 |
Data are expressed as mean±SD and median (minimum-maximum); significant results are shown in bold typeface.
AKI=acute kidney injury; BMI=body mass index; BUN=blood urea nitrogen; CABG=coronary artery bypass grafting; CPB=cardiopulmonary bypass; CRP=C-reactive protein; CVA=cerebrovascular accident; EF=ejection fraction; LDL=low-density lipoprotein; MI=myocardial infarction; NLR=neutrophil-lymphocyte ratio; PLR=platelet-lymphocyte ratio; SD=standard deviation