Table 2.
Hematological parameters for the prediction of AKI for each postoperative day.
| Postoperative measurements | Day* | Non-AKI | Subsequent AKI | P-value |
|---|---|---|---|---|
| Hemoglobin (mg/dl) | 1 | 9.3 (7.4-12.1) | 8.9 (7.6-11.9) | 0.410 |
| Leukocyte count (´ 103/µL) | 1 | 12.68±3.33 | 13.13±4.35 | 0.338 |
| 2 | 11.04±3.28 | 14.14±3.15 | < 0.001 | |
| 3 | 11.01±3.17 | 15.76±1.7 | < 0.001 | |
| 4 | 10.45±3.2 | 16.05±1.57 | < 0.001 | |
| Neutrophil count (´ 103/µL) | 1 | 11.04±3.28 | 12.28±3.03 | < 0.001 |
| 2 | 10.50±2.93 | 13.59±1.58 | 0.008 | |
| 3 | 8.48±2.83 | 14.44±2.70 | < 0.001 | |
| 4 | 8.23±2.93 | 15.45±2.43 | < 0.001 | |
| Lymphocyte count (´ 103/µL) | 1 | 0.93±0.39 | 0.58±0.22 | < 0.001 |
| 2 | 0,83 (0.03-2.63) | 0.28 (0.25-0.85) | < 0.001 | |
| 3 | 1.40 (0.01-3.6) | 0.45 (0,30-2.1) | 0.001 | |
| 4 | 1.51±0.06 | 0.75±0.09 | 0.139 | |
| Platelet count (´ 103/µL) | 1 | 179.43±49.41 | 156.07±48.29 | < 0.001 |
| 2 | 176.69±51.25 | 131.20±30.48 | < 0.001 | |
| 3 | 174.04±52.18 | 148.11±47.27 | < 0.001 | |
| 4 | 283.32±105.36 | 134.74±50.72 | 0.006 | |
| NLR | 1 | 12.91±6.24 | 23.38±8.48 | < 0.001 |
| 2 | 12.95±6.24 | 32.98±11.95 | < 0.001 | |
| 3 | 5.65 (1.97-119) | 52.66 (4.91-58.76) | < 0.001 | |
| 4 | 5.3 (-4-78) | 61.8 (51.7-72.6) | 0.001 | |
| Delta-NLR | 1 | 10.28±6.21 | 20.09±8.55 | < 0.001 |
| 2 | 9.24 (-3.38-41,72) | 39.5 (6.18-45.4) | < 0.001 | |
| 3 | 3.22 (-2-115.69) | 48.16 (2.96-51.26) | < 0.001 | |
| 4 | 2.89 (-7.58-74.69) | 57.3 (37.5-61.4) | 0.001 | |
| PLR | 1 | 217.84±91.4 | 288.39±89.6 | < 0.001 |
| 2 | 215.26±97.56 | 362.31±114.16 | < 0.001 | |
| 3 | 117.17 (22.5-2490) | 446.66 (86.19-6357.56) | < 0.001 | |
| 4 | 185.89 (-112-2982.66) | 467.6 (366.4-845.6) | 0.001 | |
| Days ** | Non-AKI | AKI | P-value | |
| Peak NLR | 01/4 | 12.20 (2.77-119) | 22.31 (17-61.8) | < 0.001 |
| Peak delta-NLR | 01/4 | 11.9 (0-115) | 20.82 (15.7-58.9) | < 0.001 |
| Peak PLR | 01/4 | 250.71 (87.50-2982.66) | 332.05 (107.57-1601.6) | < 0.001 |
| Nadir platelet count | 01/4 | 160.25 (65-320) | 141 (31-264) | 0.001 |
*
The postoperative day when the hematological parameters were obtained. The number of patients who are in the subsequent AKI group were: n=69 for day one, n=21 for day two, n=9 for day three, and n=4 for day four, while no change occurred in the non-AKI group (n=320).
**
Nadir platelet counts and peak NLR, delta-NLR, and PLR values in the first four days after surgery are compared with the occurrence of AKI during hospital stay.
AKI=acute kidney injury; NLR=neutrophil-lymphocyte ratio; PLR=platelet-lymphocyte ratio