Table 1.

Withdrawal and Continuation Method of Antithrombotic Agents in Endoscopic Ultrasound-Guided Biliary Drainage

Aspirin	Continuation
Thienopyridine derivatives	Withdraw for 5 days and replaced with aspirin
Antiplatelet agents other than thienopyridine	Withdraw for 1 day
Warfarin	PT-INR greater than the therapeutic range
	Withdraw for 3 days with replacement by intravenous heparin (10,000–20,000 units/day)
	Stop intravenous heparin 4–6 hr before EUS-BD
DOACs	Withdraw from 24 hr before EUS-BD

DOACs, direct oral anticoagulants; EUS-BD, endoscopic ultrasound-guided biliary drainage; PT-INR, prothrombin time-international normalized ratio.