Table 3.
Correlation coefficients r of executive oculomotor parameters with neuropsychological ECAS scores (total and single sections) in presymptomatic ALS gene carriers
ALS gene carriers | C9orf72 carriers | SOD1 carriers | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Anti-saccades error rate/% | Delayed saccades error rate/% | Number of voluntary gaze shifts | Intrusion rate/°/s | Anti-saccades error rate/% | Delayed saccades error rate/% | Number of voluntary gaze shifts | Intrusion rate/°/s | Anti-saccades error rate/% | Delayed saccades error rate/% | Number of voluntary gaze shifts | Intrusion rate/°/s | |
ECAS total | − 0.59 | − 0.32 | 0.46 | − 0.33 | − 0.74 | − 0.53 | 0.28 | − 0.56 | − 0.68 | − 0.13 | 0.59 | − 0.14 |
ECAS verbal memory | − 0.42 | − 0.14 | 0.29 | − 0.11 | − 0.73 | − 0.38 | 0.10 | − 0.23 | − 0.50 | − 0.02 | 0.33 | 0.05 |
ECAS visuospatial function | − 0.36 | − 0.34 | 0.19 | − 0.56 | − 0.35 | − 0.39 | 0.17 | − 0.63 | – | 0.20 | 0.19 | − 0.20 |
ECAS language | − 0.29 | − 0.18 | 0.24 | − 0.15 | − 0.54 | − 0.40 | 0.21 | − 0.54 | -0.42 | − 0.12 | 0.33 | 0.05 |
ECAS verbal fluency | − 0.43 | − 0.22 | 0.35 | − 0.28 | − 0.42 | − 0.20 | 0.33 | − 0.41 | − 0.68 | − 0.30 | 0.45 | − 0.19 |
ECAS executive function | − 0.63 | − 0.37 | 0.55 | − 0.42 | − 0.73 | − 0.67 | 0.30 | − 0.62 | − 0.77 | − 0.07 | 0.82 | − 0.30 |
The matrix represents the correlation of anti-saccade error rate, the error rate of delayed saccades, number of voluntary gaze shifts, and the saccadic intrusion rate with the total ECAS score and the following ECAS sections: verbal memory, visuospatial function, language, verbal fluency, and executive function. Significance: unbold, p > 0.05; italics, p < 0.05; bold, p < 0.01