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. 2021 Mar 11;268(9):3390–3399. doi: 10.1007/s00415-021-10510-z

Table 3.

Correlation coefficients r of executive oculomotor parameters with neuropsychological ECAS scores (total and single sections) in presymptomatic ALS gene carriers

ALS gene carriers C9orf72 carriers SOD1 carriers
Anti-saccades error rate/% Delayed saccades error rate/% Number of voluntary gaze shifts Intrusion rate/°/s Anti-saccades error rate/% Delayed saccades error rate/% Number of voluntary gaze shifts Intrusion rate/°/s Anti-saccades error rate/% Delayed saccades error rate/% Number of voluntary gaze shifts Intrusion rate/°/s
ECAS total − 0.59  − 0.32 0.46  − 0.33 − 0.74  − 0.53 0.28  − 0.56  − 0.68  − 0.13 0.59  − 0.14
ECAS verbal memory  − 0.42  − 0.14 0.29  − 0.11 − 0.73  − 0.38 0.10  − 0.23  − 0.50  − 0.02 0.33 0.05
ECAS visuospatial function  − 0.36  − 0.34 0.19 − 0.56  − 0.35  − 0.39 0.17  − 0.63 0.20 0.19  − 0.20
ECAS language  − 0.29  − 0.18 0.24  − 0.15  − 0.54  − 0.40 0.21  − 0.54 -0.42  − 0.12 0.33 0.05
ECAS verbal fluency  − 0.43  − 0.22 0.35  − 0.28  − 0.42  − 0.20 0.33  − 0.41  − 0.68  − 0.30 0.45  − 0.19
ECAS executive function − 0.63  − 0.37 0.55  − 0.42 − 0.73  − 0.67 0.30  − 0.62  − 0.77  − 0.07 0.82  − 0.30

The matrix represents the correlation of anti-saccade error rate, the error rate of delayed saccades, number of voluntary gaze shifts, and the saccadic intrusion rate with the total ECAS score and the following ECAS sections: verbal memory, visuospatial function, language, verbal fluency, and executive function. Significance: unbold, p > 0.05; italics, p < 0.05; bold, p < 0.01