Table 2.

Key findings for neurofilament heavy in progressive multiple sclerosis—all eligible studies

Summary of key findings—NFH
	Supports	Against
NFH is higher in PMS compared to RRMS—all	Three studies, 116 RRMS vs. 88 PMS	Four studies, 130 RRMS vs. 85 PMS
NFH is associated with current EDSS	Three studies, n = 217	Two studies, n = 79
NFH is associated with future disability	One study, n = 70	One study, n = 31

NFH neurofilament heavy, RRMS relapsing–remitting multiple sclerosis, PMS progressive multiple sclerosis, EDSS expanded disability status scale