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. 2021 Jan 25;14(5):555–567. doi: 10.1007/s40271-020-00491-y

Table 3.

Estimated effects of the intervention by incentive arms and the incremental effect of outcome-based incentivea (N = 240)

Source: Author calculations using the data collected from the study

Incentive arms Incremental effect of outcome-based vs. process-based incentives
Process Outcome Estimate [95% CI]
Primary outcome
  Mean change in HbA1c at month 6 − 1.04 − 1.10 − 0.05 [− 0.42 to 0.31]
Secondary outcomes
 Mean no. of glucose readings within acceptable range (out of 3 tests) during the last week of intervention 0.44 0.51 0.07 [− 0.21 to 0.34]
 Mean no. of glucose readings (out of 3 tests) during the last week of intervention 1.20 1.14 − 0.06 [− 0.45 to 0.32]
 Mean no. of medication adherent days during the last week of intervention 2.02 1.38 − 0.64 [− 1.32 to 0.04]
 Mean no. of physically active days during the last week of intervention 3.12 1.76 − 1.37 [− 2.13 to −0.60]
 Mean incentive payout during the last week of intervention 5.43 6.21 0.79 [− 1.62 to 3.19]
 Mean time (in minutes) taken by the intervention during the last week of intervention 15.74 12.91 − 2.84 [− 4.84 to −0.83]
Exploratory outcomes
 Proportion of participants who titrated up their oral medication during the intervention 0.43 0.36 − 0.08 [− 0.22 to 0.07]
 Proportion of participants who switched to insulin treatment during the intervention 0.05 0.05 0.00 [− 0.07 to 0.07]
 Mean change in EQ-5D-5L at month 6 0.03 − 0.01 − 0.04 [− 0.07 to −0.004]
 Mean change in BIPQ at month 6 − 0.78 − 3.09 − 2.31 [− 4.92 to 0.31]
 Mean change in BIPQ Treatment Control score at month 6 0.35 0.51 0.16 [− 0.42 to 0.73]
 Mean change in SMBG score at month 6 0.49 0.51 0.02 [0.10 to 0.14]
 Mean change in BMQ Specific score at month 6 0.06 0.43 0.37 [− 0.90 to 1.64]
Additional outcomes
 Proportion of participants who had improvement in HbA1c at month 6 0.82 0.80 − 0.02 [− 0.14 to 0.11]

BIPQ Brief Illness Perception Questionnaire, BMQ Beliefs about Medication Questionnaire, CI confidence interval, EQ-5D-5L European Quality of Life–5 Dimensions–5 Levels, HbA1c glycated hemoglobin, SMBQ Self-Monitoring of Blood Glucose

aCalculated as the difference in change from baseline at month 6 between that adherence outcome and process groups