Table 2.
Diagnostic yield of Qalb and CSF-TP
All patients (n = 110) | SM-GBS (n = 68) | M-GBS (n = 16) | S-GBS (n = 12) | MFS (n = 6) | Loc-GBS (n = 8) | |
---|---|---|---|---|---|---|
Median time from onset to LP (IQR) | 5 (3–10) | 5 (3–9.75) | 5 (2–10.25) | 6.5 (3–17) | 3 (2–5) | 4 (1.25–10.75) |
Median cell count (cells/µL) (IQR) | 2 (1–4) | 3 (2–4) | 2 (1–5) | 2 (1–5) | 2 (1–3) | 2 (1–6) |
Median Qalb (IQR) | 9.3 (5.6–14.3) | 10.3 (6.3–16.6) | 7.7 (4.2–16.8) | 8.9 (4.7–13.3) | 4.3 (3.7–5.7) | 9.3 (3.9–12.4) |
Above age-adjusted URL (Reiber’s equation [1]) |
65% | 72% | 56% | 58% | 0% | 75% |
Above age-adjusted URL (Hegen’s equation [2]) |
47% | 50% | 44% | 50% | 0% | 63% |
Median CSF-TP g/L (IQR) | 0.58 (0.39–0.87) | 0.61 (0.44–0.97) | 0.48 (0.30–1.09) | 0.61 (0.40–0.83) | 0.32 (0.27–0.38) | 0.59 (0.29–0.71) |
Above 0.45 g/L | 66% | 72% | 63% | 67% | 0% | 63% |
Above age-adjusted |
49% | 54% | 38% | 50% | 0% | 63% |
Qalb and CSF-TP levels are shown as well as the rate of patients with values above the upper reference limits. CSF cerebral spinal fluid, GBS Guillain–Barre syndrome, IQR interquartile range, LP lumbar puncture, M motor, MFS Miller Fisher syndrome, loc localized, SM sensorimotor, CSF-TP CSF total protein, URL upper reference limit