Table 2.
Demographic and clinical data for final validation cohort
| All Samples | Control | PD | MSA (C: P:mixed) | |
|---|---|---|---|---|
| Total samples | 154 | 51 | 53 | 50 (33:13:4) |
| Agea (range) | 67.3 ± 9.8 (40–88) | 66.6 ± 8.9 (44–88) | 72.0 ± 10.2 (40–88) | 62.9 ± 7.9 (47–79) |
| Sex (male:female) | 82:72 | 23:28 | 33:20 | 26:24 |
| Disease duration in yearsa (range) | 6.9 ± 4.1 (1–26) | 8.1 ± 3.8 (2–20) | 5.6 ± 4.0 (1–26) | |
| Race/ethnicityb | Asc – 8 | As – 1 | As – 1 | As – 6 |
| B – 4 | B – 0 | B – 0 | B – 4 | |
| H – 22 | H – 10 | H – 11 | H – 1 | |
| HN – 0 | HN – 0 | HN – 0 | HN – 0 | |
| NA – 5 | NA – 1 | NA – 4 | NA – 0 | |
| ND – 6 | ND –4 | ND –1 | ND –1 | |
| W – 109 | W – 35 | W – 36 | W – 38 | |
| UPDRSd motor (range) | 26.0 ± 13.3 (0–49) | |||
| H&Yd (range) | 2.3 ± 0.9 (0–5) | 2.3 ± 0.8 (0–4) | 3.0 ± 2.8 (1–5) | |
| MMSEd (range) | 27.6 ± 2.3 (18–30) | 28.0 ± 1.7 (24–30)e |
aMean ± SD. bAs—Asian; B—Black; H—Hispanic; HN—Hispanic, non-White; NA—Native American, ND—non-disclosed; W—White. cUndefined Asian—8. dUPDRS—Unified Parkinson's disease rating scale, H&Y—Höhn and Yahr rating scale, MMSE—Mini-Mental State Examination. eConverted from Montreal Cognitive Assessment (MoCA) according to Lawton et al. [36]