Table 1.
Variable | Mean (SD) or count (%) |
---|---|
Demographics | |
Age | 66.74 (9.22) |
Education, years | 9.66 (4.09) |
Sex, male | 53 (58.90%) |
Clinical features | |
Age at onset | 61.63 (9.72) |
Disease duration, years | 5.25 (2.92) |
UPDRS-III | 27.33 (9.57) |
Hoehn and Yahr stage | 2.00 (0.37) |
LEDD total (mg/day) | 516.82 (233.37) |
LEDDDA (mg/day) | 71.23 (106.27) |
LEDDL-DOPA (mg/day) | 386.16 (259.29) |
Behavioural measures | |
Fatigue Severity Scale | 3.47 (1.88) |
Beck Depression Inventory | 8.91 (7.45) |
Parkinson Anxiety Scale | 11.92 (9.26) |
Apathy Evaluation Scale | 31.74 (7.55) |
Parkinson’s disease sleep scale | 114.95 (22.23) |
Epworth Sleepiness Scale | 5.77 (4.19) |
Cognitive assessment | |
MoCA total | |
Raw score | 20.02 (4.87) |
Adjusted scorea | 22.46 (4.31) |
Adjusted Z scorea | 0.18 (1.42) |
MoCA adjusted subscoresa | |
Memory | 1.29 (1.47) |
Visuospatial abilities | 0.68 (1.40) |
Executive functions | 0.78 (1.77) |
Attention, and WM | 5.01 (1.03) |
Language | 3.22 (1.52) |
Orientation | 5.76 (0.57) |
PD-CFRS | |
Raw | 2.42 (3.01) |
Z score | − 0.68 (2.32) |
MoCA (Z score) minus PD-CFRS (Z score) | − 0.64 (2.30) |
SD standard deviation, UPDRS Unified Parkinson’s Disease Rating Scale, LEDD levodopa equivalent daily dose, MoCA Montreal Cognitive Assessment, WM working memory, PD-CFRS Parkinson’s Disease Cognitive Functional Rating Scale
aAdjusted according to age, education, or sex