Table 1.
Baseline characteristics
| n = 1005 | |
|---|---|
| Age [mean (SD)] | 57.9 (9.7) |
| Female gender | 1002 (99.7) |
| Pathological tumor stagea | |
| 0 | 4 (0.4) |
| In situ | 34 (3.4) |
| 1 | 456 (45.4) |
| 2 | 246 (24.5) |
| 3 | 56 (5.6) |
| 4 | 18 (1.8) |
| Unknown | 191 (19) |
| Type of surgery | |
| Breast-conserving surgery | 731 (72.7) |
| Mastectomy without breast reconstruction | 180 (17.9) |
| Autologous breast reconstruction | 36 (3.6) |
| Implant breast reconstruction | 29 (2.9) |
| Breast reconstruction, unknown type | 17 (1.7) |
| Unknown | 12 (1.2) |
| Axillary surgerya | |
| Axillary lymph node dissection | 257 (25.5) |
| Sentinel Node Procedure | 569 (56.6) |
| Other | 10 (1.0) |
| No axillary treatment/unknown | 169 (16.8) |
| Systemic treatment | |
| Chemotherapy alone | 161 (16.0) |
| Hormonal therapy alone | 106 (10.5) |
| Both chemotherapy and hormonal therapy | 464 (46.2) |
| No adjuvant treatment | 241 (24.0) |
| Unknown | 33 (3.3) |
| Smoking | |
| Never | 455 (45.3) |
| Current smoker | 134 (13.3) |
| Previous smoker | 413 (41.1) |
| Unknown | 3 (0.3) |
| Diabetes Mellitus | |
| Yes | 83 (8.3) |
| No | 922 (91.7) |
| Body Mass Index (median (IQR))b | 27.4 (7.1) |
| Unknown | 228 (25.3) |
| Type of radiation therapy | |
| Local | 336 (33.4) |
| Locoregional | 264 (26.3) |
| Unknown | 405 (40.3) |
| Radiotherapy boostc | |
| Yes | 372 (39.4) |
| No | 396 (37.0) |
| Unknown | 237 (23.6) |
| Radiotherapy fractionationd | |
| 6–12 fractions | 15 (1.5) |
| 15–19 fractions | 231 (23.0) |
| 21–24 fractions, with boost | 176 (17.5) |
| 20–25 fractions, no boost | 122 (12.1) |
| > 26 fractions | 88 (8.8) |
| Unknown | 373 (37.1) |
| Previous radiotherapy breast/chest walla | |
| Yes | 51 (5.1) |
| No | 699 (69.6) |
| Unknown | 255 (25.4) |
| Months since radiotherapy [median (IQR)] | 22 (35) |
Numbers are shown as n(%) unless stated otherwise. Continuous outcomes are shown as mean (SD) when normally distributed and median(IQR) otherwise
SD standard deviation, IQR interquartile range
aTotal other than 100% due to rounding
bCalculated as weight/height2
cAn additional radiotherapy boost on the tumor bed or axillary/lymph node boost
dDose per fraction was unknown