Table 2.

Demographic data and RRT parameters of 117 metformin-associated lactic acidosis patients admitted in ICUs and treated with renal replacement therapy (modified from Ref. [45])

Patients no. (F/M)	76/41 (64.9%)
ICU survival (survived/dead, %)	92/25 (78.6%)
Age (years, mean)	71.6
At RRT start
Creatinine (umol/L, mean)	598.8
pH (arterial blood, mean)	7.04
Lactate (mmol/L, mean)	12
Time interval before RRT start (hours, mean)	3.2
RRT clinical parameters
Duration of RRT (days, mean)	3.9
Dialysis dose (ml/Kg/day, mean)	977.7
Predilution (% of infusion, mean)	31.8
Heparin anticoagulant	84/19 (81.5%)
HF or HDF techniques (yes/no (%))	91/18 (83.4%)
CRRT or PIRRT modalities (yes/no (%))	87/22 (79.8%)

RRT renal replacement therapy, HF hemofiltration, HDF hemodiafiltration, CRRT continuous renal replacement therapy, PIRRT prolonged intermittent renal replacement therapy